Xanthones III and V prevented the glutathione reductase (GR) activity reduction induced by FeSO
in brain homogenates. Forebrain homogenates were incubated with 5 μM FeSO4 and 2.5 μM xanthones III or V in Kreb’s buffer. Control is represented by 100%. Mean values ± S.E.M. of three experiments per group are shown. The data are represented as a percentage with respect to control. aP < 0.01 vs control; bP < 0.01vs. FeSO4.