Effect of xanthone III on the ROS production induced by FeSO
in homogenates of different tissues. a) Forebrain, b) liver and c) kidney homogenates were incubated with 5 μM FeSO4 and different concentrations on xanthone III (0 – 2.5 μM) in Kreb’s buffer. Control is represented by 100% and EtOH (50%) was used as a vehicle to dissolve xanthones. In all panels, mean values ± S.E.M. of six experiments per group are shown. aP < 0.01 vs. control; bP < 0.01 vs. FeSO4.