Table 1 Effect of selected medicinal plants on apoptosis induced by STZ in RINm5F cells

Cell control

8.18 ± 1.41

52.46 ±6.99

26.419 ±2.56

Cells + Pe (2.5 μg/ml)

11.81 ±2.98

52.03 ±17.41

27.51 ± 9.19

Cells + Pe (5 μg/ml)

11.51 ±2.98

51.25 ±3.22

27.75 ±3.53

Cells + Pe (10 μg/ml)

16.03 ±4.52^*

48.01 ±8.50

25.60 ±4.66

Cells + Pe (25 μg/ml)

17.39 ±1.82

49.05 ±5.53

25.97 ±1.96

Cells + Pe (50 μg/ml)

18.33 ±1.62^*

45.79 ±3.17

28.47 ±1.99

Cells + Pe (100 μg/ml)

20.63 ±1.60^***

44.01 ±2.35

26.29 ±1.58

Cells + STZ

25.48 ± 3.77^***

39.13 ±6.69^*

36.18 ±8.48

Cells + Pe (2.5 μg/ml) + STZ

19.25 ±3.45

41.25 ±6.69

31.02 ±8.75

Cells + Pe (5 μg/ml) + STZ

15.29 ±4.05^$$$

37.86 ±6.77

34.75 ±8.34

Cells + Pe (10 μg/ml) + STZ

11.77 ±2.31^$$$

45.28 ±5.61

29.13 ±7.98

Cells + Pe (25 μg/ml) + STZ

16.04 ±1.42^$$$

38.65 ±3.43

35.40 ±2.99

Cells + Pe (50 μg/ml) + STZ

18.34 ±1.23^$

36.89 ±4.33

29.86 ±5.26

Cells + Pe (100 μg/ml) + STZ

23.35 ±1.80

36.90 ±4.15

30.29 ±4.29

Cell control

9.58 ± 2.48

56.03 ± 2.65

25.51 ± 2.05

Cells + Cl (2.5 μg/ml)

11.05 ± 2.89

51.28 ± 3.32

26.82 ± 4.27

Cells + Cl (5 μg/ml)

10.36 ± 3.94

51.24 ± 2.88

28.41 ± 3.41

Cells + Cl (10 μg/ml)

10.94 ± 3.78

51.75 ± 5.09

28.81 ± 4.81

Cells + Cl (25 μg/ml)

12.98 ± 2.72

46.02 ± 7.77

30.61 ± 1.71

Cells + Cl (50 μg/ml)

14.7 ± 2.06

48.61 ± 4.63

31.94 ± 2.61

Cells + STZ

23.37 ± 4.51^***

41.38 ± 7.44

32.21 ± 6.86

Cells + Cl (2.5 μg/ml) + STZ

17.14 ± 4.75^$$

41.94 ± 5.02

31.21 ± 8.91

Cells + Cl (5 μg/ml) + STZ

15.77 ± 5.13^$$$

40.82 ± 2.87

32.73 ± 7.59

Cells + Cl (10 μg/ml) + STZ

12.74 ± 3.07^$$

44.60 ± 3.09

29.62 ± 7.73

Cells + Cl(25 μg/ml) + STZ

18.74 ± 2.44

42.42 ± 1.93

35.47 ± 1.38

Cells + Cl (50 μg/ml) + STZ

19.13 ± 3.99

40.18 ± 3.48

32.40 ± 1.67

Cell control

5.87 ± 1.70

53.22 ± 11.81

26.98 ± 7.17

Cells + Tc 2.5 μg/ml

7 ± 1.57

57.79 ± 13.81

23.90 ± 6.57

Cells + Tc 5 μg/ml

5.92 ± 1.91

59.32 ± 13.48

23.98 ± 7.96

Cells + Tc 10 μg/ml

7.12 ± 2.22

57.12 ± 12.35

24.58 ± 7.44

Cells + Tc 25 μg/ml

7.62 ± 2.17

57.13 ± 3.45

25.73 ± 6.11

Cells + Tc 50 μg/ml

7.07 ± 2.44

60.44 ± 3.89

20.03 ± 5.79

Cells + Tc 100 μg/ml

10.16 ± 5.27

56.95 ± 2.47

28.68 ± 0.69

Cells + STZ

24.69 ± 2.19^***

40.01 ± 9.17^*

26.28 ± 1.67

Cells + Tc 2.5 μg/ml + STZ

26.69 ± 1.34

51.35 ± 6.22

18.73 ± 8.09

Cells + Tc 5 μg/ml + STZ

25.86 ± 1.83

35.08 ± 10.81

34.82 ± 6.61

Cells + Tc 10 μg/ml + STZ

21.65 ± 3.34

43.86 ± 9.22

25.21 ± 8.91

Cells + Tc 25 μg/ml + STZ

16.77 ± 3.65^$$

43.48 ± 2.13

31.36 ± 3.86

Cells + Tc 50 μg/ml + STZ

14.16 ± 1.69^$

42.86 ± 6.94

28.54 ± 6.12

Cells + Tc 100 μg/ml + STZ

14.05 ± 1.80^$$

48.64 ± 1.3

36.12 ± 1.78

Cell control

11.87 ± 3.70

53.22 ± 11.81

26.98 ± 7.17

Cells + Gb (1 μg/ml)

12.6 ± 2.39

49.79 ± 9.11

26.87 ± 6.33

Cells + STZ

28.5 ± 8.85^***

40.24 ± 6.71^*

28.42 ± 8.30

Cells + STZ + Gb (1 μg/ml)

19.91 ± 5.05^$

47.3 ± 5.92

25.84 ± 3.12