From: In vitro cytocidal effects of the essential oil from Croton cajucara (red sacaca) and its major constituent 7- hydroxycalamenene against Leishmania chagasi
Substance tested
L. chagasi
Cytotoxicity [μg/mL]
MIC [μg/mL]
IC50[μg/mL]
Essential oil
250
66.7
>500
7-hydroxycalamenene purified fraction
15.6
1.37
Amphotericin B
0.625
0.01
14.6