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Table 5 IC 50 (μg/ml) values of crude and fractionated extracts of Alpinia pahangensis against selected cell lines

From: Antioxidant potential, cytotoxic activity and total phenolic content of Alpinia pahangensis rhizomes

Extract/ fraction Inhibition concentration, IC50(μg/ml)
  KB MCF7 A549 Ca Ski HCT 116 HT-29 MRC-5
Methanol >100 >100 >100 >100 >100 >100 >100
Hexane 5.8 ± 0.1 22.0 ± 1.3 16.6 ± 0.2 18.4 ±0.2 9.1 ± 2.0 16.9 ± 0.5 17.3 ± 0.5
Ethyl acetate 10.2 ± 0.3 50.3 ± 0.3 25.9 ± 1.4 35.3 ± 2.0 19.9 ± 1.1 38.4 ± 0.4 44.0 ± 3.0
Water >100 >100 >100 >100 >100 >100 >100
Doxorubicin 0.46 ± 0.02 0.088 ± 0.01 1.01 ± 0.02 0.31 ± 0.10 0.41 ± 0.07 0.56 ± 0.05 0.69 ± 0.05
  1. Each value is expressed as mean ± standand deviation of triplicate measurements.
  2. Data are expressed as IC50 in μg/ml which is the concentration of extract requires to inhibit cell growth by 50%).