From: Guava pomace: a new source of anti-inflammatory and analgesic bioactives
Groups | Dose (mg/kg) | Histamine (1 h) | Serotonin (1 h) | ||
---|---|---|---|---|---|
Mean Edema (∆V mL) | Percent inhibition | Mean Edema (∆V mL) | Percent inhibition | ||
1 h | 1 h | ||||
Control | 0.12 ± 0.02 | 0.07 ± 0.02 | |||
Cyproheptadine | 2 | 0.04 ± 0.02** | 65 | 0.02 ± 0.02* | 65 |
GPE | 300 | 0.07 ± 0.02* | 38 | 0.02 ± 0.02* | 68 |
GPE | 100 | 0.07 ± 0.01* | 41 | 0.02 ± 0.01* | 62 |
GPE | 30 | 0.13 ± 0.01 | - | 0.03 ± 0.03 | 51 |