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Table 3 Effect of i.p. administration of guava pomace extract (GPE) on a dextran-induced paw edema

From: Guava pomace: a new source of anti-inflammatory and analgesic bioactives

Groups

Dose (mg/kg)

Mean Edema (∆V mL)

  

1 h

2 h

Control

 

0.12 ± 0.02

0.10 ± 0.04

Cyproheptadine

2

0.04 ± 0.02***

0.05 ± 0.03*

GPE

300

0.03 ± 0.02***

0.03 ± 0.02**

GPE

100

0.08 ± 0.02

0.07 ± 0.02

GPE

30

0.09 ± 0.02

0.15 ± 0.04

  1. ∆V = the values represent the mean difference of paw volume between the basal measure and others measures (1 and 2 h) ± S.E.M.; n = 5-6. *p < 0.05, **p < 0.01, ***p < 0.001, significantly different when compared to control (ANOVA followed by Dunnett’s test).