Table 2 Induction of apoptosis by the plant extracts and sinapinic acid in HeLa cells
Apoptotic cells | Extracts/Compounds | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Solvent control (DMSO; 0.05%) | Positive control (Camptothecin; 0.1 mg/mL) | Ethanolic extract | Phenolic-rich extract | Sodium butyrate | Sinapinic acid | |||||
0.7 mg/mL | 1.4 mg/mL | 0.7 mg/mL | 1.4 mg/mL | 4.5 mM | 9.0 mM | 4.5 mM | 9.0 mM | |||
Number of Early Apoptotic cells (%) | 0.95 ± 0.35 | 91.65 ± 3.75 | 6.40 ± 3.11 | 42.90 ± 4.81 | 20.70 ± 6.65 | 78.90 ± 5.09 | 3.75 ± 1.06 | 7.60 ± 1.27 | 4.40 ± 1.27 | 8.40 ± 1.55 |
Number of Late Apoptotic cells (%) | 0.20 ± 0.14 | 3.55 ± 1.06 | 2.05 ± 0.92 | 4.15 ± 0.07 | 3.50 ± 1.84 | 4.15 ± 2.05 | 1.00 ± 0.28 | 2.05 ± 1.06 | 1.75 ± 0.78 | 3.25 ± 1.06 |