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Table 4 Percent reduction in the number of regenerated protoplasts in the Trichophyton rubrum strains

From: Trans-chalcone and quercetin down-regulate fatty acid synthase gene expression and reduce ergosterol content in the human pathogenic dermatophyte Trichophyton rubrum

Compound (ÎŒg/mL)

Strain

 
 

MYA3108

ΔTruMDR2

MIC of quercetin

30.26 ± 5.78 b

91.66 ± 8.33d

MIC of cerulenin

100c

100e

MIC of trans-chalcone

100c

100e

0.5 MIC of quercetin

0a

36.19 ± 6.44a

0.5 MIC of cerulenin

100c

65.26 ± 7.61b

0.5 MIC of trans-chalcone

100c

83.24 ± 3.50c

  1. MIC: minimum inhibitory concentration.
  2. a, b, c, d: Values followed by different superscript letters differ significantly between groups.