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Table 3 Percent reduction of ergosterol content in the Trichophyton rubrum strains

From: Trans-chalcone and quercetin down-regulate fatty acid synthase gene expression and reduce ergosterol content in the human pathogenic dermatophyte Trichophyton rubrum

Concentration (ÎŒg/mL)

Strain MYA3108

ΔTruMDR2

MIC of quercetin

33.54 ± 8.95a

56.15 ± 4.06 a

MIC of cerulenin

40.72 ± 5.6a

49.48 ± 8.24 a

MIC of fluconazole

40.95 ± 9.05a

61.50 ± 6.73a

MIC of trans-chalcone

100 b

100 b

0.5 MIC of trans-chalcone

74.59 ± 5.35 c

77.85 ± 15.73 c

  1. MIC: minimum inhibitory concentration.
  2. a, b, c: Values followed by different superscript letters differ significantly between groups.
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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