Th immunohistochemical staining of superoxide dismutase (SOD), malondialdehyde (MDA), 8-hydroxy-2′-deoxyguanosine (8-OHdG), and osteopontin (OPN) in the kidney of the rat on day 14. All the images represent serial sections. EG, EG + catechin2.5, EG + catechin10.0 represent rats administered with EG or EG and catechin at 0, 2.5, and 10.0 mg/kg/day, respectively. Strong expression of SOD was could be observed in the control group, but SOD was not detected in EG group. The expression of SOD was slightly lower in EG + catechin 2.5 group than that in EG + catechin10.0 group. OPN was barely detectable in the control group, but it was strongly expressed in the EG group. The OPN expression in EG + catechin2.5 group was slightly higher than that in EG + catechin10.0 group. MDA was undetectable in the control group and EG + catechin groups, but it was detectable in EG group kidneys. The expression of 8-OHdG was undetectable in the control group, but it was detectable in the EG group. And the expression of 8-OHdG was nearly undetectable in the EG + catechin groups.