Table 3 Effect of Melastoma malabathricum leaves extract on blood glucose levels in STZ-induced diabetic rats

1

Fasting plasma glucose (mg/dL)

81.8 ± 0.969

277 ± 2.608^***

132.6 ± 1.965^*

108.2 ± 2.922^**

86.2 ± 1.428^***

90.6 ± 0.509^***

2

Fasting Plasma Insulin (μU/mL)

14.2 ± 0.583

3.6 ± 0.509^***

6.8 ± 0.584^*

10.4 ± 0.601^**

13 ± 0.316^***

12.6 ± 0.411^***

3

Glycated Heamoglobin (A1c) (%)

1.32 ± 0.073

4.86 ± 0.151^***

3.72 ± 0.081^*

2.96 ± 0.678^**

2.04 ± 0.129^***

2.16 ± 0.107^***

4

Hexokinase (μg/mg of tissue)

147.8 ± 3.484

90.4 ± 3.203^***

115.6 ± 1.631^*

131 ± 1.871^**

142.6 ± 2.015^***

140.4 ± 2.182^***

5

Glucose-6-Phosphatase (unit/mg of tissue)

9 ± 0.707

14.2 ± 0.583^***

13.4 ± 0.509^*

11.6 ± 0.611^**

8.6 ± 0.712^***

9.8 ± 0.567^***

6

Fructose-1-6-biphosphatase (unit/mg of tissue)

28.8 ± 0.861

55 ± 1.012^***

43.8 ± 1.158^*

38.2 ± 1.068^**

30 ± 0.707^***

31.8 ± 0.861^***

7

Total Cholesterol (mg/dl)

78.2 ± 2.011

128 ± 2.366^***

113.2 ± 2.782^*

101.4 ± 1.631^**

87 ± 1.703^***

89.2 ± 1.393^***

8

Triglycerides (mg/dl)

81.4 ± 1.327

134.8 ± 1.356^***

115.4 ± 1.077^*

103.6 ± 1.503^**

90 ± 0.707^***

93.4 ± 1.077^***

9

HDL Cholesterol (mg/dL)

53.2 ± 2.478

28.6 ± 2.441^***

41 ± 1.732^*

44.8 ± 1.158^**

53.8 ± 0.861^***

52.8 ± 1.655^***

10

LDL Cholesterol (mg/dL)

8.92 ± 2.149

72.84 ± 2.812^***

50.72 ± 3.355^*

34.08 ± 1.979^**

15.4 ± 2.302^***

19.52 ± 1.547^***

11

VLDL Cholesterol (mg/dL)

16.28 ± 0.265

26.96 ± 0.271^***

23.08 ± 0.215^*

20.72 ± 0.301^**

18 ± 0.141^***

18.68 ± 0.215^***

12

Weight Variation (g)

192.6 ± 0.872

157.8 ± 1.625^***

189.4 ± 1.032^***

186.4 ± 1.749^***

197 ± 1.304^***

194.2 ± 1.393^***