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Table 1 Effects of single medicinal herb of SHT on the cell viability and tyrosinase activity

From: Ssanghwa-tang, an oriental herbal cocktail, exerts anti-melanogenic activity by suppression of the p38 MAPK and PKA signaling pathways in B16F10 cells

Treatment Concentration (μg/ml) Viability (%) Tyrosinase activity (%)
    No stimulation α-MSH stimulation
Control 0 100.0 ± 2.3 100.0 ± 4.6 287.7 ± 7.1
P. lactiflora 140 104.5 ± 1.8 130.8 ± 7.6 322.5 ± 8.2
A. gigas 56 101.2 ± 0.6 126.6 ± 2.5 306.8 ± 3.3
A. membranaceus 56 108.2 ± 1.3 152.9 ± 8.1 370.6 ± 5.0
C. officinale 56 100.0 ± 1.1 96.5 ± 3.2 276.1 ± 1.1
R. glutinosa 56 108.5 ± 0.8 101.7 ± 4.9 282.9 ± 1.1
G. glabra 41.9 102.3 ± 0.3 122.5 ± 1.1 374.6 ± 9.0
C. cassia 22.3 106.8 ± 0.6 140.4 ± 6.9 338.8 ± 3.6
Z. officinale 41.9 104.3 ± 1.4 86.3 ± 9.2 207.6 ± 5.5**
Z. jujube 29.9 100.5 ± 0.2 78.9 ± 3.6* 246.2 ± 2.8**
SHT 500 104.4 ± 2.4 58.9 ± 5.5* 100.5 ± 3.1**
  1. The data are representative of two independent experiments carried out in triplicate, and expressed as mean ± SD. *p < 0.05 vs control, **p < 0.05 vs α-MSH-treated cells.