Antidiarrhoeal and antimicrobial activity of Calpurnia aurea leaf extract

Table 1 Effect of Calpurnia aurea extract on castor oil induced diarrhea in mice

Treatment	Dose, (mg/kg,p.o.)	Time of onset of diarrhea(min.)	Total number of faeces in 4 h(frequency of defecation in 4 h)	% Inhibition of defecation	Weight of stool(g)
Group I		91 ± 10.9	8.2 ± 1.5	-	0.72 ± 0.07
Group II	3	237.8 ± 2.0^b	1 ± 0.3^b	87.80	0.04 ± 0.05^b
Group III	100	145.2 ± 15.3^a	4.8 ± 0.9^a	41.46	0.30 ± 0.08^b
Group IV	200	193 ± 14.5^b	3.2 ± 0.2^c	60.98	0.20 ± 0.05^b
Group IV	400	212.4 ± 11.3^b	1.4 ± 0.2^b	82.93	0.01 ± 0.04^b

Significantly different when compared with that of the control at ^aP < 0.05, ^bP < 0.001, ^cP < 0.01, results are mean ± SEM.

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