Figure 2

Behavioral indicators changed during the CUS procedure and after curcumin treatment. ( A ) Body weight changed during the 3 weeks of chronic unpredictable stress (CUS). ***P < 0.0001 shows the CUS group (n = 13) vs. control group (n = 14). (B) and (C) Sucrose preference and sucrose consumption after 3 weeks of CUS and after 1 month of treatment. *P < 0.05, **P < 0.01 shows the CUS group (n = 13) vs. control group (n = 14). ^# P < 0.05 shows model group (n = 6) vs. control group (n = 14). ⁺ P < 0.05 shows treatment group (n = 7) vs. model group (n = 6). (D) and (E) Open-field test indexes (total distance travelling and the number of rearing events) after 3 weeks of CUS and after 1 month of treatment. *P < 0.05, **P < 0.01 shows CUS group (n = 13) vs. control group (n = 14). ^# P < 0.05 shows model group (n = 6) vs. control group (n = 14). ⁺ P < 0.05 shows treatment group (n = 7) vs. model group (n = 6).