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Table 3 Genotoxic activity expressed by the mean and the standard deviation (SD) of the Olive Tail Moment (OTM) and percentage DNA in comet tail (% DNA) in MCF10A cells treated with nemorosone for 3 and 24 hours and controls

From: Evaluation of estrogenic, antiestrogenic and genotoxic activity of nemorosone, the major compound found in brown Cuban propolis

 

OTM

%DNA

OTM

%DNA

 

Mean ± SD

Mean ± SD

Mean ± SD

Mean ± SD

Treatments

  3 hours

 

  24 hours

 

Control

1.90±2.56

9.80±10.17

1.78±2.18

10.93±4.27

DMSO

2.27±1.25

9.92±8.99

2.53±2.07

15.27±4.78

10-9M

1.95±2.42

8.10±9.17

2.27±1.50

11.78±3.16

10-8M

1.64±2.52

8.31±9.70

1.84±0.29

13.04±5.25

10-7M

1.26±1.44

7.67±5.70

1.48±0.28

10.23±7.91

10-6M

1.63±2.07

8.23±8.79

2.44±3.62

13.46±4.52

10-5M

1.58±2.14

7.76±8.31

1.83±2.40

11.38±3.87

  1. Negative control: Culture Medium (DMEM).
  2. DMSO: Solvent control (0.01%).