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Table 3 Changes in the organ weight of rats Wistar after acute oral treatment with Dioscorea villosa at a daily dose of 5 g/Kg (single dose)

From: Bioassay-guided evaluation of Dioscorea villosa – an acute and subchronic toxicity, antinociceptive and anti-inflammatory approach

    Groups
Organs FC FT MC MT
Heart 0.4729 ± 0.015 0.4543 ± 0.011 0.4114 ± 0.010 0.3929 ± 0.015
Lungs 0.7343 ± 0.024 0.6700 ± 0.027 0.5529 ± 0.023 0.4786 ± 0.025
Liver 3.309 ± 0.1047 3.506 ± 0.1595 2.947 ± 0.080 2.960 ± 0.1238
Brain 0.7671 ± 0.022 0.8757 ± 0.022** 0.4914 ± 0.027 0.5414 ± 0.031
Kidneys 0.8071 ± 0.021 0.8271 ± 0.030 0.8329 ± 0.043 0.7671 ± 0.030
Stomach 0.8671 ± 0.032 0.7771 ± 0.015* 0.6571 ± 0.024 0.5686 ± 0.030*
Uterus/ovaries 0.4629 ± 0.089 0.7486 ± 0.097 - -
Pancreas 0.4843 ± 0.092 0.5614 ± 0.060 0.3371 ± 0.097 0.3786 ± 0.043
  1. FC control female, FT treated female, MC control male, MT treated male. Data are expressed as mean ± S.D., n = 6; * Significant difference from control group ( *p < 0.05, **p < 0.01 and ***p < 0.001) (test t).