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Figure 4 | BMC Complementary and Alternative Medicine

Figure 4

From: Particled Mica, STB-HO has chemopreventive potential via G1 arrest, and inhibition of proliferation and vascular endothelial growth factor receptor 2 in HCT colorectal cancer cells

Figure 4

Effect of STB-HO on VEGF production and MMP-9 secretion in HCT116 cells. HCT116 Cells were treated with or without STB-HO (0, 250 or 500 μg/ml) for 48 h. (A) STB-HO inhibits vascular endothelial growth factor (VEGF) production. VEGF level was measured by ELISA. After removal of the supernatant, HCT116 cells were washed by PBS. The cells were cultured in completed RPMI media for 48 h. Then VEGF level was measured by ELISA. (B) STB-HO inhibits matrix metalloproteinase (MMP-9) production. MMP-9 level was measured by ELISA. Data are presented as means ± S.D. * p < 0.05, ** p < 0.01 and *** p < 0.001 compared to untreated control.

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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