Effects of GTPs on plasma membrane translocation of PKCα at the early stage of brain ischemia were determined by specific PKCα assay. Quantification of PKC activity in the membrane-to-cytosol ratio was expressed as a fold increase relative to the vehicle group of ischemia at 0 min. Data represent the means ± SD (n = 6, each). **
P < 0.01 vs. vehicle group of ischemia 0 min. ##
P < 0.01 vs. vehicle group at the same time points.