Effects of GTPs on BBB permeability at the early stage of cerebral ischemia were assessed by Evans blue dye leakage. Experiment groups are saline-treated (vehicle) groups and GTPs-treated groups at the time points of 0, 30, 60, and 120 min after ischemia, respectively. (A) representative images of brain sections in the groups of ischemia and GTPs-treated groups of ischemia at 120 min. (B) Evans blue content is expressed as a fold increase relative to the vehicle group of ischemia at 0 min. Data are given as the means ± SD (n = 8, each). **
P < 0.01 vs. vehicle group of ischemia 0 min. ##
P < 0.01 vs. vehicle group at the same time points.