RETRACTED ARTICLE: Gastroprotective effect of desmosdumotin C isolated from Mitrella kentii against ethanol-induced gastric mucosal hemorrhage in rats: possible involvement of glutathione, heat-shock protein-70, sulfhydryl compounds, nitric oxide, and anti-Helicobacter pylori activity

Table 2 Gastroprotective effect of desmosdumotin C against ethanol-induced ulceration and observed liver function test

Animal group	Pre-treatment 5 ml/kg	Mucus weight	Ulcer area	Inhibition (%)	ALT	AST
Animal group	Pre-treatment 5 ml/kg	Mucus weight	Ulcer area	Inhibition (%)	(IU/L)	(IU/L)
A	Normal control	2.9 ± 0.2 *	0.00	0.00	36.57 ± 1.67*	230 ± 9.81 *
B	ulcer control	0.98 ± 0.3	557.28 ± 6.2	NA	56.5 ± 2.71	293 ± 2.15
C	Omeprazole (20 mg/kg)	1.55 ± 0.2*	108 ± 7.7 *	79.07	48.2 ± 2.5 *	275.7 ± 6.01 *
D	DES (5 mg/kg)	1.37 ± 0.5 *	168.48 ± 9 * $	69.77	51 ± 1.47 *	283.6 ± 4.39 *
E	DES (10 mg/kg)	2.09 ± 0.1 *#$	54.72 ± 3.8* $	90.18	32 ± 2.8 *#$	240.04 ± 3.79 *$#
F	DES (20 mg/kg)	1.5 ± 0.4 *	74.88 ± 10.3 *$	86.56	34.2 ± 1.6 *$	257.4 ± 9.22*$

NA, not applicable; AST, Aspartate transaminase; ALT, Alanine Aminotranferase. All values are represented as mean (n = 3–5 animals) ± standard error mean, * indicates (p < 0.05) compared to ulcer control. $ indicates (p < 0.05) statistical differences compared to omeprazole group.

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