Figure 3

Effects of XJEK on myocardial fibrosis, perivascular fibrosis, and cardiac Hyp content in 2K1C rats. (A) Representive figure of myocardial fibrosis (VG staining, ×400); (B) Representive figure of perivascular fibrosis (VG staining, ×400); (C) Statistic results of myocardial fibrosis; (D) Statistic results of perivascular fibrosis; (E) Statistic results of cardiac Hyp content in cardiac tissue. Group divided ibidem. Levels of myocardial and perivascular fibrosis, and the cardiac Hyp content all increased significantly compared with the Sh-Op group. XJEK at all doses for 4 weeks could reverse these pathological changes, as well as the positive control fosinopril. Data are expressed as mean ± SD, n = 8 ~ 11. ^* P < 0.05, ^** P < 0. 01 vs Sh-Op group; ^# P < 0.05, ^## P < 0.01 vs model group.