Figure 2

Effects of XJEK on HW/BW, myocyte CSA of cardiac tissue in 2K1C rats. (A) Representive figure of myocyte cross-section (HE staining, ×400); (B) Representive figure of myocyte long axis (HE staining, ×400); (C) Statistic results of HW/BW; (D) Statistic results of myocyte CSA. 1: Sh-Op group; 2: model group; 3:2K1C + XJEK 6 g/kg group; 4:2K1C + XJEK12g/kg group; 5: 2K1C + XJEK 24 g/kg group; 6:2K1C + fosinopril 15 mg/kg group. The HW/BW ratios, myocyte CSA increased significantly compared with the Sh-Op group. XJEK at all doses for 4 weeks could reverse these pathological changes, as well as the positive control fosinopril. Data are expressed as mean ± SD, n = 8 ~ 11. ^** P < 0. 01 vs Sh-Op group; ^# P < 0.05, ^## P < 0.01 vs model group.