Anti-HIV-1 activity, protease inhibition and safety profile of extracts prepared from Rhus parviflora

Table 1 In vitro cytotoxicity and anti-HIV activity of the extracts derived from leaves of R. parviflora using TZM-bl and CEM-GFP cells

Plant extract	CC₅₀(μg/ml)*	IC₅₀(μg/ml)*	TI
	TZM-bl cells
50% Ethanolic extract	331	26	12.7
Aqueous extract	383	15	25.5
	CEM-GFP cells
50% Ethanolic extract	196	29	6.8
Aqueous extract	643	65	9.9

*CC₅₀: The cytotoxic concentration of the extracts that caused the reduction of viable cells by 50%. All data presented are averages of duplicate experiments.
*IC₅₀: The concentration of the extracts that resulted in 50% inhibition in HIV infection. All data presented are averages of duplicate experiments.
TI: Therapeutic index is CC₅₀/IC_50.

ISSN: 2662-7671