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Table 2 Anti-dermatophytic activity (zone of inhibition and MIC) of Xylosma longifolium extracts compared with commercial antibiotic 16 μg/ml Amphotericin-B

From: Antioxidant and anti-dermatophytic properties leaf and stem bark of Xylosma longifolium clos

Part of plant

Extracts

Anti-dermatophytic activity

MB

MC-1

MC-2

MG

TA

TR-1

TR-2

Leaf

PE

A

-

10±1.3c

13±1.4c

13±1.6d

10±1.4c

-

-

B

>9

2.25

1.125

1.125

2.25

>9

>9

CH

A

10±1.6d

10±1.3c

14±1.6d

-

11±1.2c

-

-

B

2.25

2.25

0.562

>9

2.25

>9

>9

ME

A

10±1.2c

13±1.3c

14±1.3c

-

19±1.5c

-

10±1.1c

B

2.25

1.125

2.25

>9

0.140625

>9

2.25

Bark

PE

A

-

-

15±1.2c

10±1.4c

12±1.2c

10±1.4c

10±1.4c

B

>9

>9

0.5625

2.25

2.25

2.25

2.25

CH

A

-

-

10±1.3c

14±1.4c

12±1.5c

11±1.3c

12±1.4c

B

>9

>9

2.25

0.5625

2.25

2.25

1.125

ME

A

-

-

13±1.2c

13±1.2c

15±1.4c

12±1.2c

14±1.3c

B

>9

>9

2.25

2.25

0.28125

2.25

1.125

Amphotericin-B

A

16±0.9b

17±1.0b

19±1.0b

19±0.8b

20±1.1c

16±0.9b

18±1.1c

B

1

0.125

0.06

0.25

<0.06

0.25

0.125

DMSO

-

-

-

-

-

-

-

 
  1. A –The values (average of triplicate) are radial of zone of inhibition at 9 mg/ml; B – MIC (mg/ml) mean value n = 3, P < 0.05.
  2. PE – Petroleum ether; CH – Chloroform; ME - Methanol.
  3. Microsporum boullardii MTCC 6059 - MB; M. canis MTCC 2820 - MC-1; M. canis MTCC 3270 - MC-2; M. gypseum MTCC 2819 - MG; Trichophyton ajelloi MTCC 4878 -TA; T. rubrum MTCC 296 - TR-1; T. rubrum MTCC 3272 - TR-2; – no activity.
  4. Means ± SD of triplicates. For each column, values followed by one or more of the same letters were not significant different at P < 0.05.