| NA | NS | OVA | PANE | |
---|---|---|---|---|---|
 |  |  |  | 0.05% | 0.1% |
Body weight (g) | Â | Â | Â | Â | Â |
Day 1 | 24.5 ± 0.8 | 24.1 ± 0.7 | 23.9 ± 0.5 | 25.0 ± 0.7 | 24.4 ± 0.6 |
Day 49 | 28.6 ± 0.5 | 27.5 ± 0.5 | 27.4 ± 0.4 | 27.4 ± 0.7 | 27.1 ± 0.5 |
Spleen weight (mg) | 88.4 ± 3.5 | 84.9 ± 4.5 | 91.0 ± 2.8 | 87.6 ± 3.6 | 93.0 ± 2.7 |
Spleen index | 3.0 ± 0.1 | 3.0 ± 0.1 | 3.2 ± 0.1 | 3.1 ± 0.1 | 3.3 ± 0.1 |
Spleen cellularity (%) | Â | Â | Â | Â | Â |
CD4+ | 26.4 ± 0.2 | 26.7 ± 0.8 | 25.6 ± 1.2 | 25.7 ± 1.3 | 26.0 ± 1.4 |
CD8+ | 10.6 ± 0.4 | 11.0 ± 0.6 | 11.0 ± 0.3 | 11.5 ± 0.6 | 10.6 ± 0.5 |
B220+ | 55.1 ± 1.5 | 55.2 ± 1.9 | 55.8 ± 3.5 | 55.5 ± 2.6 | 56.6 ± 3.3 |
CD11b+ | 4.2 ± 0.4 | 4.9 ± 0.2 | 4.3 ± 0.1 | 4.3 ± 0.1 | 4.4 ± 0.3 |