PANE attenuated the infiltration of inflammatory cells and crypt hyperplasia in the duodenum of OVA-sensitized and challenged BALB/c mice. Mice were treated as the protocol described in the Methods section. Representative sections of the duodenum stained with H&E were shown (original magnification, ×100). Six measurements per section were counted and the villus/crypt ratio was measured. Data are expressed as mean ± SE of 11 mice per group pooled from 3 independent experiments. #, p < 0.05 compared to the NS group. *, p < 0.05 compared to the OVA group.