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Figure 7 | BMC Complementary and Alternative Medicine

Figure 7

From: The protective effect of geniposide on human neuroblastoma cells in the presence of formaldehyde

Figure 7

Geniposide regulates apoptotic-related genes expressions. Geniposide was able to regulate not only mRNA levels ( A ) but also protein levels of Bcl-2 ( B ) to antagonize formaldehyde-induced SH-SY5Y cell impairment. SH-SY5Y cells were incubated with formaldehyde and geniposide for 24 h. The expression of Bcl-2, P53, caspase 3 and caspase 9 mRNA were measured by quantitative real time PCR ( C ). Treatment conditions were as described in Figure 2. Cells treated with formaldehyde alone and those with no treatment were used as positive and negative controls, respectively. Gp, geniposide. Data are expressed as the mean ± SD from three independent experiments. *P < 0.05, vs. the group treated with formaldehyde alone. The Gel electrophoresis is representative of three independent experiments.

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