Effect of CSP-AU1 on EAE. C57BL/6 mice were treated i.p. daily with 50 mg/kg of CSP-AU1 (○) or PBS (●), starting on day 4 after immunization with MOG35-55 peptide. The average score of 14 mice per group is shown, and statistically significant differences (* p<0.05) between EAE mice treated with PBS or fraction CSP-AU1 are indicated. A representative experiment of two independent experiments is shown.