Figure 5From: 2,3-cis-2R,3R-(−)-epiafzelechin-3-O-p-coumarate, a novel flavan-3-ol isolated from Fallopia convolvulus seed, is an estrogen receptor agonist in human cell lines Potency curves of phytoestrogens rhodoeosein and emodin in human ovarian carcinoma BG1Luc4E2 cells. ●= E2; ○ = rhodoeosein; ▼ = emodin; Δ = genistein. Rhodoeosein was able to superinduce luciferase activity in BG1Luc4E2 cells. Luciferase activity was expressed as a percent of the maximum induction by E2 (1 nM) and was determined in cell lysates 24 h after treatment. Incubation of cells with 0.25, 0.316, and 1 mM rhodoeosein caused cell death and these values were not included in above analysis. Values represent the mean ± SD of triplicate determinations.Back to article page