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Table 7 Effect of aqueous extract of Terminalia paniculata on apoptotic markers in CCl 4 -treated Chang liver cells

From: Toxicological evaluation of Terminalia paniculata bark extract and its protective effect against CCl4-induced liver injury in rodents

Groups Phospho-p53 p53 Cleaved caspase-3 Phospho-Bad Bad Cleaved PARP
Normal control 0.134 ± 0.037 0.129 ± 0.020 0.126 ± 0.023 0.141 ± 0.024 0.146 ± 0.040 0.135 ± 0.042
TPW (50 μg/ml) control 0.130 ± 0.025 0.131 ± 0.028 0.123 ± 0.020 0.136 ± 0.033 0.152 ± 0.059 0.138 ± 0.066
CCl 4 control 1.896 ± 0.081* 2.069 ± 0.054* 2.182 ± 0.091* 1.758 ± 0.037* 2.367 ± 0.072* 2.211 ± 0.101*
TPW (25 μg/ml) + CCl 4 1.384 ± 0.066*,# 1.514 ± 0.033*,# 1.487 ± 0.040*,# 1.324 ± 0.051*,# 1.868 ± 0.064*,# 1.445 ± 0.047*,#
TPW (50 μg/ml) + CCl 4 1.193 ± 0.050*,# 1.148 ± 0.057*,# 1.075 ± 0.072*,# 1.219 ± 0.035*,# 1.644 ± 0.049*,# 1.117 ± 0.053*,#
  1. All values are expressed as mean ± SEM and experiments were carried out in triplicate. * p < 0.05 vs. normal control; # p < 0.05 vs. CCl4 control. The levels of the apoptotic markers were expressed in terms of absorbance as per kit’s protocol.