|
Groups
|
Phospho-p53
|
p53
|
Cleaved caspase-3
|
Phospho-Bad
|
Bad
|
Cleaved PARP
|
|---|
|
Normal control
|
0.134 ± 0.037
|
0.129 ± 0.020
|
0.126 ± 0.023
|
0.141 ± 0.024
|
0.146 ± 0.040
|
0.135 ± 0.042
|
|
TPW (50
μg/ml) control
|
0.130 ± 0.025
|
0.131 ± 0.028
|
0.123 ± 0.020
|
0.136 ± 0.033
|
0.152 ± 0.059
|
0.138 ± 0.066
|
|
CCl
4
control
|
1.896 ± 0.081*
|
2.069 ± 0.054*
|
2.182 ± 0.091*
|
1.758 ± 0.037*
|
2.367 ± 0.072*
|
2.211 ± 0.101*
|
|
TPW (25
μg/ml) + CCl
4
|
1.384 ± 0.066*,#
|
1.514 ± 0.033*,#
|
1.487 ± 0.040*,#
|
1.324 ± 0.051*,#
|
1.868 ± 0.064*,#
|
1.445 ± 0.047*,#
|
|
TPW (50
μg/ml) + CCl
4
|
1.193 ± 0.050*,#
|
1.148 ± 0.057*,#
|
1.075 ± 0.072*,#
|
1.219 ± 0.035*,#
|
1.644 ± 0.049*,#
|
1.117 ± 0.053*,#
|
- All values are expressed as mean ± SEM and experiments were carried out in triplicate. *
p < 0.05 vs. normal control; #
p < 0.05 vs. CCl4 control. The levels of the apoptotic markers were expressed in terms of absorbance as per kit’s protocol.
