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Table 5 Effect of the aqueous extract of Terminalia paniculata and silymarin on the hepatic enzyme activities in CCl 4 -treated rats

From: Toxicological evaluation of Terminalia paniculata bark extract and its protective effect against CCl4-induced liver injury in rodents

Groups

AST (U/L)

ALT (U/L)

ALP (U/L)

BilT (mg/dl)

Normal control

107.55 ± 4.65

49.05 ± 1.30

25.87 ± 3.52

0.10 ± 0.03

CCl 4 control (CCl 4 1 ml/kg, i.p.)

589.04 ± 10.12#

298.21 ± 10.55#

175.51 ± 6.84#

1.05 ± 0.12#

Silymarin (100 mg/kg, p.o.)

243.02 ± 8.80*

107.72 ± 8.24*

48.63 ± 15.30*

0.23 ± 0.11*

TPW

(400 mg/kg, p.o.)

272.33 ± 26.8*

131.27 ± 5.31*

65.66 ± 5.24*

0.30 ± 0.10*

  1. TPW aqueous extract of Terminalia paniculata, AST asparate transferase; ALT alanine transferase, ALP alkaline phosphatase, BilT – total bilirubin.
  2. Data represented as mean ± S.E.M (n = 6), analysed by one-way ANOVA followed by Dunnett’s post hoc test. # p < 0.05 as compared to normal control, *p < 0.05 as compared to CCl4 group.
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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