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Figure 2 | BMC Complementary and Alternative Medicine

Figure 2

From: Toxicological evaluation of Terminalia paniculata bark extract and its protective effect against CCl4-induced liver injury in rodents

Figure 2

Photomicrographs of histological changes of rat liver at magnification of 10×. (A) normal control showed well maintained histology of rat liver (−); (B) CCl4 treated control rats showed lymphocyte infiltration (red arrow), fatty changes (blue arrow) and liver cell hypertrophy with congestion of hepatic sinusoids (green arrow) (+++); (C) Silymarin (100 mg/kg, p.o.) + CCl4 (1.0 ml/kg in olive oil 1:1, i.p.) treated group showed scarce lymphocyte infiltration and preserved cell architecture (+); (D) TPW (400 mg/kg, p.o.) + CCl4 (1.0 ml/kg in olive oil 1:1, i.p.) treated rat liver showed improved structure with mild lymphocyte infiltration (+). Scoring was performed as follows: –, no injury; +++, severe injury; ++, moderate injury; +, mild injury.

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