Skip to main content

Table 2 Inhibition of yeast and mammalian α-glucosidases by the crude aqueous extracts and fractions of the fruits of F. deltoidea from two different varieties

From: Antidiabetic and antioxidant properties of Ficus deltoidea fruit extracts and fractions

Substrate

α-glucosidases inhibitory activities, IC50(mg/ml)

SF (var. angustifolia)

BF (var. kunstleri)

Acarbose

SFC

SFE

SFW

BFC

BFE

BFW

Yeast α-glucosidase

       

p NPG

0.065 ± 0.005a

0.259 ± 0.014b

0.083 ± 0.006a

0.061 ± 0.003c

0.225 ± 0.008d

0.049 ± 0.003e

9.075 ± 0.065

Rat intestinal α-glucosidase

       

Sucrose

0.552 ± 0.013a

0.611 ± 0.020a

0.473 ± 0.011b

0.538 ± 0.016c

0.596 ± 0.015c

0.444 ± 0.004d

0.039 ± 0.001

p NPG

7.226 ± 0.389a

13.957 ± 0.238b

7.173 ± 0.170a

6.407 ± 0.102c

10.040 ± 0.291d

4.123 ± 0.136e

0.058 ± 0.001

  1. Each value is expressed as a mean ± SD of triplicates from three different experiments. Values with different superscript letters between the same variety, within the same row are significantly different at p < 0.01. SFC, SFE and SFW indicate crude aqueous extract, ethyl acetate fraction and water fraction of SF (var. angustifolia). BFC, BFE and BFW indicate crude aqueous extract, ethyl acetate fraction and water fraction of BF (var. kuntsleri).