From: Histone modifications and traditional Chinese medicinals
Histone/DNA modification | Enzymes | Position/abbreviation* | Conformation | Reference |
---|---|---|---|---|
cytosine methylation | DNA methyltransferase | DNMT | heterochromatic | [24] |
histone acetylation | histone acetyltransferase | HAT | euchromatic | [2] |
histone deacetylation | histone deacetylase | HDAC | heterochromatic | [2] |
histone methylation | histone methyltransferase | H3K4 | euchromatic | [25] |
H3K36 | euchromatic | |||
H3K79 | euchromatic | |||
H3R17 | euchromatic | |||
H3K9 | heterochromatic | |||
H3K27 | heterochromatic | |||
H4K20 | heterochromatic | |||
histone demethylation | histone demethylase | H3K4i | heterochromatic | [26] |
H3K36i | heterochromatic | |||
H3R2i | heterochromatic | |||
H4R3i | heterochromatic | |||
H3K27i | euchromatic | |||
histone phosphorylation | mitogen- and stress-activated protein kinase (MSK), I kappa B alpha kinase (IKK) | H3S10 | euchromatic | [27] |
histone de-phosphorylation | MAP kinase phosphatase (MKP) | H3S10i | heterochromatic | [28] |
ATP-dependent chromatin remodeling | ATP-dependent chromatin remodeling complex | ATP | hetero- or euchromatic | [29] |