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Table 3 Selectivity index values of the hexane crude extract and isolated compounds from M. undata

From: Antimicrobial activity and cytotoxicity of triterpenes isolated from leaves of Maytenus undata (Celastraceae)

 

Selectivity index values (LC50/MIC)

 

C. albicans

C. neoformans

E. coli

E. faecalis

S. aureus

P. aeruginosa

Hexane extract

0.25

3.80

0.63

0.95

0.12

0.25

Compound 1 1

NC2

NC

NC

NC

NC

NC

Compound 3

NC

NC

NC

NC

NC

NC

Compound 5

0.096

0.13

0.19

0.19

NC

0.17

Compound 6

0.047

0.063

0.12

0.047

NC

0.093

  1. 1 friedelin (1), friedelan-3β-ol (2), taraxerol (3), 3-oxo-11α-methoxyolean-12-ene-30-oic acid (4), 3-oxo-11α-hydroxyolean-12-ene-30-oic acid (5), 3,11-dihydroxyolean-12-ene-30-oic acid (6).
  2. 2NC = not calculated.