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Table 2 Antibacterial and antifungal activities of the crude extracts and the fractions expressed as minimum inhibitory concentration (μg/ml)

From: Evaluation of pharmacological activities, cytotoxicity and phenolic composition of four Maytenus species used in southern African traditional medicine to treat intestinal infections and diarrhoeal diseases

 

Maytenus peduncularis

Maytenus procumbens

Microbial spp

CrE

Hex

DCM

ETOAc

But

Water

CrE

Hex

DCM

ETOAc

But

Water

E. c

312

39

39

78

625

>2500

1250

39

39

156

1250

>2500

E. f

312

39

39

156

1250

>2500

>2500

39

39

156

625

>2500

P. a

312

19

19

156

312

>2500

312

78

39

156

625

>2500

S. a

>2500

78

39

312

78

>2500

1250

39

78

312

625

>2500

C. a

312

312

78

312

156

312

1250

156

39

156

312

625

C. n

78

312

78

78

1250

2500

625

156

39

156

156

2500

A. f

312

78

156

156

312

625

1250

78

78

78

156

625

 

Maytenus senegalensis

Maytenus undata

Microbial spp

CrE

Hex

DCM

ETOAc

But

Water

CE

Hex

DCM

ETOAc

But

Water

E. c

2500

78

78

156

1250

>2500

1250

312

156

156

>2500

>2500

E. f

2500

39

39

312

625

>2500

312

156

156

312

2500

>2500

P. a

625

39

78

156

1250

>2500

312

78

78

78

2500

>2500

S. a

625

78

39

156

625

>2500

625

156

156

156

312

>2500

C. a

1250

78

39

156

156

625

1250

625

78

312

625

1250

C. n

156

156

39

78

78

1250

156

1250

78

78

312

2500

A. f

625

156

78

156

1250

312

1250

625

625

156

625

625

 

Controls

Microbial spp

Gent

Amp B

70% ace

Distilled Water

        

E. c

0.39

-

>2500

>2500

        

E. f

0.78

-

>2500

>2500

        

P. a

1.56

-

>2500

>2500

        

S. a

0.78

-

>2500

>2500

        

C. a

-

6.25

>2500

>2500

        

Microbial spp

Gent

Amp B

70% ace

Distilled Water

        

E. c

0.39

-

>2500

>2500

        
  1. N.B: E. c = Escherichia coli, E. f = Enterococcus faecalis, P. a = Pseudomonas aeruginosa, S. a = Staphylococcus aureus, C. a = Candida albicans, C. n = Cryptococcus neoformans, A. f = Aspergillus fumigatus, Gent = gentamicin, Amp B = amphotericin B, .CrE = crude extract, Hex = hexane fraction, DCM = dichloromethane, ETOAc = ethyl acetate and But = n- Butanol.