Effects of Astragalus polysaccharides on P-glycoprotein efflux pump function and protein expression in H22 hepatoma cells in vitro

Table 2 Intracellular fluorescence intensity of Rh-123 accumulation in H22/ADM cells (n = 6)

Group	Fluorescence intensity (mean ± SD)
	24 h	48 h	72 h
RFP 10 μmol/L	87.49 ± 1.26^★	133.71 ± 1.59^▴	131.41 ± 1.54
Control group	114.77 ± 1.16	198.51 ± 0.69	136.18 ± 1.32
APS 0.8 mg/L	135.52 ± 0.92^★	255.14 ± 0.61^▴	137.40 ± 2.01
APS 4 mg/L	257.38 ± 0.97^★	266.32 ± 2.03^▴	250.32 ± 1.80^●
APS 20 mg/L	357.34 ± 0.80^★	285.75 ± 1.30^▴	367.35 ± 1.31^●
APS 100 mg/L	342.83 ± 0.94^★	307.42 ± 1.12^▴	460.04 ± 1.74^●
APS 500 mg/L	701.30 ± 1.14^★	345.27 ± 1.84^▴	458.43 ± 0.63^●
VER 10 μmol/L	928.04 ± 1.17^★	706.04 ± 2.02^▴	657.91 ± 1.28^●

^★ P < 0.05, vs. Control group (24 h); ^▴ P < 0.05, vs. Control group (48 h); ^● P < 0.05, vs. Control group (72 h).