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Table 6 Effects of SAME on histology of liver

From: Hepatoprotective activity of Sonchus asper against carbon tetrachloride-induced injuries in male rats: a randomized controlled trial

Treatment

Fatty changes

Cellular aggregation hypertrophy

Blood vessel congestion

Inflammatory cells infiltrations

Control

-

-

-

-

3 ml/kg CCl4

+++

++

++

+++

100 mg/kg SAME + CCl4

-

−/+

-

−/+

200 mg/kg SAME + CCl4

-

-

-

-

100 mg/kg Silymarin + CCl4

-

-

-

-

200 mg/kg SAME alone

-

-

-

-

  1. -, normal; +/−, mild; ++, medium; +++, severe disruption.