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Table 6 Effects of SAME on histology of liver

From: Hepatoprotective activity of Sonchus asper against carbon tetrachloride-induced injuries in male rats: a randomized controlled trial

Treatment Fatty changes Cellular aggregation hypertrophy Blood vessel congestion Inflammatory cells infiltrations
Control - - - -
3 ml/kg CCl4 +++ ++ ++ +++
100 mg/kg SAME + CCl4 - −/+ - −/+
200 mg/kg SAME + CCl4 - - - -
100 mg/kg Silymarin + CCl4 - - - -
200 mg/kg SAME alone - - - -
  1. -, normal; +/−, mild; ++, medium; +++, severe disruption.