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Table 3 Effect of SAME on antioxidant defense system in rat liver

From: Hepatoprotective activity of Sonchus asper against carbon tetrachloride-induced injuries in male rats: a randomized controlled trial

Treatment CAT SOD GST GR GSH-Px
  (U/min) (U/mg protein) nmol/min/mg protein nmol/min/mg protein nmol/min/mg protein
Control 4.8 ± 0.10++ 22.7 ± 1.18++ 192 ± 2.49++ 127.3 ± 10.5++ 84.2 ± 5.9++
3 ml/kg CCl4 2.9 ± 0.06** 11.9 ± 0.38** 104 ± 2.4** 62.33 ± 9.28** 46 ± 3.6**
100 mg/kg SAME + CCl4 4.04 ± 0.09++ 16.2 ± 0.38*++ 142 ± 2.6*++ 90.2 ± 11.3*++ 61 ± 6.6*++
200 mg/kg SAME + CCl4 4.8 ± 0.125++ 20.4 ± 0.37++ 190 ± 2.9++ 112.3 ± 6.5++ 75 ± 4.2++
100 mg/kg Silymarin + CCl4 4.9 ± 0.116++ 22.9 ± 0.57++ 201 ± 2.5++ 134.3 ± 5.7++ 84 ± 4.0++
200 mg/kg SAME alone 4.96 ± 0.05++ 24.7 ± 0.38++ 199 ± 2.19++ 132.3 ± 6.96++ 87 ± 3.5++
  1. Mean ± SE (n = 6 number).
  2. *, ** Significance from the control group at P < 0.05 and P < 0.01 probability level.
  3. ++ Significance from the CCl4 group at P < 0.01 probability level.