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Table 1 Effect of SAME on liver function test in rat

From: Hepatoprotective activity of Sonchus asper against carbon tetrachloride-induced injuries in male rats: a randomized controlled trial

Treatment ALT AST ALP LDH (nmol/min/
  (U/L) (U/L) (U/L) mg protein)
Control 52. ± 2.12++ 76 ± 2.74++ 198 ± 3.93++ 48.3 ± 2.38++
3 ml/kg CCl4 111 ± 3.42** 234.0 ± 4.27** 470.3 ± 6.49** 77.6 ± 2.46**
100 mg/kg SAME + CCl4 91 ± 3.23**++ 136 ± 4.91**++ 347.7 ± 10.7**++ 66 ± 3.76**+
200 mg/kg SAME + CCl4 56 ± 1.35++ 97.5 ± 2.90**++ 217.8 ± 3.91*++ 53 ± 2.61++
100 mg/kg Silymarin + CCl4 58 ± 2.68++ 102.3 ± 4.99**++ 227.5 ± 3.89**++ 50 ± 4.08++
200 mg/kg SAME alone 50 ± 2.14++ 75.5 ± 3.26++ 195.3 ± 4.11++ 46 ± 2.38++
  1. Mean ± SE (n = 6 number).
  2. ** Significance from the control group at P < 0.01 probability level.
  3. ++ Significance from the CCl4 group at P < 0.01 probability level.