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Table 9 Effect of DAS-77 on serum electrolytes in the main study

From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats

Treatment

Dose (mg/kg)

Main study

Ā Ā 

Na+(mmol/L)

K+(mmol/L)

Clāˆ’(mmol/L)

HCO3 āˆ’(mmol/L)

Ca2+(mg/dl)

Distilled water

(10 ml/kg)

156.60ā€‰Ā±ā€‰4.44

7.52ā€‰Ā±ā€‰0.47

100.90ā€‰Ā±ā€‰3.73

10.56ā€‰Ā±ā€‰1.45

1.09ā€‰Ā±ā€‰0.05

DAS-77

80

150.30ā€‰Ā±ā€‰0.59

5.98ā€‰Ā±ā€‰0.25*

105.40ā€‰Ā±ā€‰0.38

10.13ā€‰Ā±ā€‰0.58

1.05ā€‰Ā±ā€‰0.03

DAS-77

400

152.70ā€‰Ā±ā€‰3.39

5.04ā€‰Ā±ā€‰0.10***

105.10ā€‰Ā±ā€‰0.53

12.70ā€‰Ā±ā€‰0.50

1.20ā€‰Ā±ā€‰0.03

DAS-77

2000

149.70ā€‰Ā±ā€‰0.90

5.19ā€‰Ā±ā€‰0.14***

104.70ā€‰Ā±ā€‰0.90

13.20ā€‰Ā±ā€‰0.84

1.25ā€‰Ā±ā€‰0.04*

  1. Values are meanā€‰Ā±ā€‰S.E.M. (nā€‰=ā€‰10). * pā€‰<ā€‰0.05, *** pā€‰<ā€‰0.001 vs. distilled water (One-way ANOVA followed by Dunnettā€™s posttest).