Table 8 Effect of DAS-77 on serum biochemical parameters in rats in the reversibility study

Distilled water

(10 ml/kg)

58.75 ± 2.95

7.68 ± 0.38

39.5 ± 1.68

83.13 ± 3.14

2.4 ± 0.25

1.59 ± 0.15

0.50 ± 0.18

0.65 ± 0.10

1.93 ± 0.36

93.74 ± 8.50

28.23 ± 5.48

65.88 ± 7.87

31.75 ± 3.08

5.75 ± 0.31

1.50 ± 0.27

DAS-77

80

60.11 ± 2.67

7.72 ± 0.36

40.89 ± 1.35

84.11 ± 3.25

2.18 ± 0.15

1.61 ± 0.15

0.24 ± 0.04

0.70 ± 0.08

2.36 ± 0.34

85.33 ± 5.54

20.11 ± 2.57

58.56 ± 5.26

26.67 ± 1.62

5.22 ± 0.15

1.44 ± 0.18

DAS-77

400

54.50 ± 1.05

7.41 ± 0.52

39.00 ± 1.60

85.38 ± 3.69

2.25 ± 0.33

1.61 ± 0.32

0.70 ± 0.16

0.68 ± 0.13

1.84 ± 0.28

97.75 ± 10.75

25.69 ± 3.09

51.50 ± 4.05

33.63 ± 2.06

5.38 ± 0.26

1.50 ± 0.38

DAS-77

2000

55.50 ± 2.05

7.12 ± 0.31

38.50 ± 1.34

84.67 ± 6.04

1.90 ± 0.24

1.10 ± 0.18

0.47 ± 0.09

0.70 ± 0.10

2.03 ± 0.48

111.20 ± 13.20

29.50 ± 3.47

74.50 ± 11.22

35.33 ± 4.55

5.17 ± 0.17

1.00 ± .00