Table 6 Effect of DAS-77 on hematological parameters in rats in the reversibility study
From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats
| Treatment | Dose (mg/kg) | Reversibility study | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PCV (%) | WBC (10³/μl) | N (%) | L (%) | E (%) | RBC (106/μl) | PLT (104/μl) | Hb (g/dl) | MCV (fl) | MCH (pg) | MCHC (g/dl) | ||
| Distilled water | (10 ml/kg) | 45.13 ± 1.16 | 6.91 ± 0.62 | 47.75 ± 3.06 | 51.88 ± 3.19 | 1.50 ± 0.05 | 6.93 ± 0.37 | 2.69 ± 0.22 | 14.73 ± 0.37 | 66.00 ± 2.30 | 21.53 ± 0.77 | 32.66 ± 0.03 |
| DAS-77 | 80 | 43.78 ± 1.01 | 5.18 ± 0.78 | 45.00 ± 1.88 | 53.44 ± 2.04 | 2.25 ± 0.95 | 6.59 ± 0.27 | 3.74 ± 0.13 | 14.28 ± 0.32 | 66.78 ± 1.53 | 21.83 ± 0.52 | 32.61 ± 0.07 |
| DAS-77 | 400 | 43.13 ± 1.17 | 6.39 ± 0.67 | 48.75 ± 2.26 | 50.13 ± 2.25 | 2.25 ± 0.48 | 6.28 ± 0.44 | 3.08 ± 0.14 | 14.10 ± 0.39 | 70.63 ± 3.99 | 23.08 ± 1.30 | 32.17 ± 0.04 |
| DAS-77 | 2000 | 45.50 ± 0.96 | 5.12 ± 0.49 | 50.00 ± 2.79 | 49.83 ± 2.81 | 1.00 ± 0.00 | 6.92 ± 0.24 | 3.93 ± 0.24 | 14.83 ± 0.31 | 66.17 ± 1.01 | 21.48 ± 0.35 | 32.60 ± 0.04 |