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Table 6 Effect of DAS-77 on hematological parameters in rats in the reversibility study

From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats

Treatment Dose (mg/kg) Reversibility study
   PCV (%) WBC (10³/μl) N (%) L (%) E (%) RBC (106/μl) PLT (104/μl) Hb (g/dl) MCV (fl) MCH (pg) MCHC (g/dl)
Distilled water (10 ml/kg) 45.13 ± 1.16 6.91 ± 0.62 47.75 ± 3.06 51.88 ± 3.19 1.50 ± 0.05 6.93 ± 0.37 2.69 ± 0.22 14.73 ± 0.37 66.00 ± 2.30 21.53 ± 0.77 32.66 ± 0.03
DAS-77 80 43.78 ± 1.01 5.18 ± 0.78 45.00 ± 1.88 53.44 ± 2.04 2.25 ± 0.95 6.59 ± 0.27 3.74 ± 0.13 14.28 ± 0.32 66.78 ± 1.53 21.83 ± 0.52 32.61 ± 0.07
DAS-77 400 43.13 ± 1.17 6.39 ± 0.67 48.75 ± 2.26 50.13 ± 2.25 2.25 ± 0.48 6.28 ± 0.44 3.08 ± 0.14 14.10 ± 0.39 70.63 ± 3.99 23.08 ± 1.30 32.17 ± 0.04
DAS-77 2000 45.50 ± 0.96 5.12 ± 0.49 50.00 ± 2.79 49.83 ± 2.81 1.00 ± 0.00 6.92 ± 0.24 3.93 ± 0.24 14.83 ± 0.31 66.17 ± 1.01 21.48 ± 0.35 32.60 ± 0.04
  1. Values are mean ± S.E.M. (n = 8). p > 0.05 vs. distilled water (One-way ANOVA followed by Dunnett’s posttest).
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