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Table 4 Effect of DAS-77 on weight of vital organs (per 100 g body weight) in the reversibility study

From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats

Treatment Dose (mg/kg) Reversibility study
   Liver Kidney Lungs Heart Testes Spleen Pancreas Brain Ovaries
Distilled water (10 ml/kg) 2.60 ± 0.11 0.57 ± 0.01 0.73 ± 0.06 0.36 ± 0.02 1.39 ± 0.13 0.29 ± 0.01 0.25 ± 0.03 0.78 ± 0.03 0.12 ± 0.00
DAS-77 80 2.53 ± 0.12 0.55 ± 0.03 0.68 ± 0.03 0.35 ± 0.02 1.21 ± 0.05 0.25 ± 0.01 0.24 ± 0.02 0.82 ± 0.04 0.10 ± 0.01
DAS-77 400 2.74 ± 0.12 0.62 ± 0.01 0.88 ± 0.0* 0.42 ± 0.03 0.95 ± 0.27 0.25 ± 0.01 0.26 ± 0.02 0.71 ± 0.04 0.12 ± 0.01
DAS-77 2000 2.79 ± 0.10 0.63 ± 0.05 0.83 ± 0.02 0.38 ± 0.03 1.35 ± 0.28 0.27 ± 0.02 0.34 ± 0.02 0.82 ± 0.04 0.14 ± 0.01
  1. Values are mean ± S.E.M (n = 10). * p < 0.05 vs. distilled water (One-way ANOVA followed by Dunnett’s posttest).
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