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Table 2 Effect of DAS-77 on sperm motility, count and morphology (% abnormality)

From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats

   Main study Reversibility study
Treatment Dose (mg/kg) Sperm motility (%) Sperm count (million/ml) Abnormality (%) Sperm motility (%) Sperm counted (million/ml) Abnormality (%)
Distilled water (10 ml/kg) 85.00 ± 6.00 31.14 ± 2.50 5.14 ± 1.10 81.60 ± 7.17 25.80 ± 4.28 7.20 ± 1.72
DAS-77 80 73.43 ± 12.61 25.57 ± 4.07 8.86 ± 2.42 72.33 ± 9.30 24.67 ± 3.53 8.33 ± 2.01
DAS-77 400 87.29 ± 12.05 33.00 ± 3.52 4.14 ± 1.44 70.80 ± 9.07 23.00 ± 2.54 7.40 ± 1.50
DAS-77 2000 42.71 ± 10.33* 14.71 ± 3.00** 12.43 ± 2.26* 74.25 ± 13.56 25.50 ± 5.52 5.50 ± 1.71
  1. Values are mean ± S.E.M (n = 7, main study; n = 5, reversibility study). * p < 0.05, ** p < 0.01 vs. distilled water (One-way ANOVA followed by Dunnett’s posttest).
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