Table 15 Effect of DAS-77 on antioxidant enzymes in rat liver in the reversibility study
From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats
Treatment | Dose (mg/kg) | Reversibility study | |||||
|---|---|---|---|---|---|---|---|
GSH (nm/mg) | SOD (u/mg) | CAT (u/mg) | Peroxidase (u/mg) | MDA (nm/mg) | Protein (mg) | ||
Distilled water | (10 ml/kg) | 1.45 ± 0.22 | 3.24 ± 0.33 | 14.94 ± 1.54 | 0.10 ± 0.10 | 0.19 ± 0.02 | 34.68 ± 1.91 |
DAS-77 | 80 | 3.69 ± 0.55*** | 5.82 ± 0.72** | 26.87 ± 3.33** | 1.83 ± 0.23** | 0.19 ± 0.02 | 24.41 ± 2.52** |
DAS-77 | 400 | 1.70 ± 0.31 | 3.62 ± 0.56 | 16.72 ± 2.58 | 1.14 ± 0.18 | 0.22 ± 0.01 | 24.35 ± 1.40* |
DAS-77 | 2000 | 2.29 ± 0.15 | 3.71 ± 0.14 | 17.10 ± 0.64 | 1.17 ± 0.04 | 0.93 ± 0.81 | 33.10 ± 3.66 |