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Table 15 Effect of DAS-77 on antioxidant enzymes in rat liver in the reversibility study

From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats

Treatment Dose (mg/kg) Reversibility study
   GSH (nm/mg) SOD (u/mg) CAT
(u/mg)
Peroxidase (u/mg) MDA (nm/mg) Protein
(mg)
Distilled water (10 ml/kg) 1.45 ± 0.22 3.24 ± 0.33 14.94 ± 1.54 0.10 ± 0.10 0.19 ± 0.02 34.68 ± 1.91
DAS-77 80 3.69 ± 0.55*** 5.82 ± 0.72** 26.87 ± 3.33** 1.83 ± 0.23** 0.19 ± 0.02 24.41 ± 2.52**
DAS-77 400 1.70 ± 0.31 3.62 ± 0.56 16.72 ± 2.58 1.14 ± 0.18 0.22 ± 0.01 24.35 ± 1.40*
DAS-77 2000 2.29 ± 0.15 3.71 ± 0.14 17.10 ± 0.64 1.17 ± 0.04 0.93 ± 0.81 33.10 ± 3.66
  1. Values are mean ± S.E.M. (n = 4). * p < 0.05, ** p < 0.01, *** p < 0.001 vs. distilled water (One-way ANOVA followed by Dunnett’s posttest).
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