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Table 14 Effect of DAS-77 on antioxidant enzymes in rat kidney in the reversibility study

From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats

Treatment Dose (mg/kg) Reversibility study
   GSH (nm/mg) SOD (u/mg) CAT (u/mg) Peroxidase (u/mg) MDA (nm/mg) Protein (mg)
Distilled water (10 ml/kg) 2.03 ± 0.37 3.30 ± 0.45 15.24 ± 2.08 1.04 ± 0.14 0.13 ± 0.01 32.56 ± 1.70
DAS-77 80 2.22 ± 0.46 3.48 ± 0.59 16.07 ± 2.70 1.09 ± 0.18 0.15 ± 0.02 30.88 ± 4.35
DAS-77 400 1.09 ± 0.14 2.04 ± 0.18 9.43 ± 0.85 0.64 ± 0.06 0.15 ± 0.02 35.49 ± 4.60
DAS-77 2000 2.31 ± 0.42 3.05 ± 0.49 14.07 ± 2.24 0.96 ± 0.15 0.14 ± 0.02 34.32 ± 5.29
  1. Values are mean ± S.E.M. (n = 5, main study). p > 0.05 vs. distilled water (One-way ANOVA followed by Dunnett’s posttest).
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