Table 14 Effect of DAS-77 on antioxidant enzymes in rat kidney in the reversibility study
From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats
Treatment | Dose (mg/kg) | Reversibility study | |||||
|---|---|---|---|---|---|---|---|
GSH (nm/mg) | SOD (u/mg) | CAT (u/mg) | Peroxidase (u/mg) | MDA (nm/mg) | Protein (mg) | ||
Distilled water | (10 ml/kg) | 2.03 ± 0.37 | 3.30 ± 0.45 | 15.24 ± 2.08 | 1.04 ± 0.14 | 0.13 ± 0.01 | 32.56 ± 1.70 |
DAS-77 | 80 | 2.22 ± 0.46 | 3.48 ± 0.59 | 16.07 ± 2.70 | 1.09 ± 0.18 | 0.15 ± 0.02 | 30.88 ± 4.35 |
DAS-77 | 400 | 1.09 ± 0.14 | 2.04 ± 0.18 | 9.43 ± 0.85 | 0.64 ± 0.06 | 0.15 ± 0.02 | 35.49 ± 4.60 |
DAS-77 | 2000 | 2.31 ± 0.42 | 3.05 ± 0.49 | 14.07 ± 2.24 | 0.96 ± 0.15 | 0.14 ± 0.02 | 34.32 ± 5.29 |