Skip to main content

Table 13 Effect of DAS-77 on antioxidant enzymes in rat kidney in the main study

From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats

Treatment Dose (mg/kg) Main study
   GSH (nm/mg) SOD (u/mg) CAT
(u/mg)
Peroxidase
(u/mg)
MDA (nm/mg) Protein (mg)
Distilled water (10 ml/kg) 1.69 ± 0.15 3.41 ± 0.73 17.66 ± 5.22 1.26 ± 0.34 0.27 ± 0.08 28.94 ± 5.64
DAS-77 80 2.76 ± 0.83 12.31 ± 3.01 58.21 ± 13.80** 3.96 ± 0.94 0.11 ± 0.03* 50.22 ± 10.34
DAS-77 400 2.12 ± 0.21 7.69 ± 0.53 35.46 ± 2.43 2.32 ± 0.15 0.07 ± 0.02** 51.13 ± 3.57
DAS-77 2000 2.17 ± 0.18 9.63 ± 1.03 44.41 ± 4.75* 3.02 ± 0.32 0.13 ± 0.03* 35.22 ± 2.57
  1. Values are mean ± S.E.M. (n = 5). * p < 0.05, ** p < 0.01 vs. distilled water (One-way ANOVA followed by Dunnett’s posttest).
\