Table 12 Effect of DAS-77 on antioxidant enzymes in rat brain in the main study
From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats
Treatment | Dose (mg/kg) | Main study | |||||
|---|---|---|---|---|---|---|---|
GSH (nm/mg) | SOD (u/mg) | CAT (u/mg) | Peroxidase (u/mg) | MDA (nm/mg) | Protein (mg) | ||
Distilled water | (10 ml/kg) | 1.35 ± 0.29 | 3.94 ± 1.26 | 18.19 ± 5.80 | 1.24 ± 0.39 | 0.23 ± 0.02 | 30.68 ± 3.80 |
DAS-77 | 80 | 1.89 ± 0.32 | 3.13 ± 0.75 | 14.44 ± 3.44 | 0.98 ± 0.23 | 0.28 ± 0.11 | 38.27 ± 6.34 |
DAS-77 | 400 | 1.68 ± 0.28 | 1.94 ± 0.28 | 8.96 ± 1.30 | 0.61 ± 0.09 | 0.18 ± 0.01 | 29.65 ± 4.47 |
DAS-77 | 2000 | 1.83 ± 0.30 | 2.38 ± 0.52 | 10.93 ± 2.42 | 0.74 ± 0.17 | 0.21 ± 0.02 | 27.47 ± 3.10 |